People tend to overthink secondary stats a lot when choosing gear. It's important to remember that item level is always king due to how strong main stat is. 9 times out of 10 you should be choosing your highest item level gear, regardless of what secondary stats it has. My rough rule for Leech/Avoidance/Sockets is that they're generally worth ~10 item levels. Below you'll find a breakdown of our stat priority for Mythic+.
Let's start with the basics
The biggest difference between Mythic+ and Raiding stat priorities is that we place a lot less emphasis on damage and more on healing, which means stats like Mastery that provide a lot of healing but no damage will be prioritized much more heavily.
For the fated season, our Season 2 Aberrus tier set has been resurrected with some tuning changes. Our 2 set got buffed by 20% while our 4 set got nerfed by 50% to offset the baseline buffs they gave Holy Prism in the last major patch:
2 Set: Holy Shock's critical strikes heal for 80% more and reduce the cooldown of Light's Hammer by 2 seconds, or Holy Prism by 1 second.
4 Set: Light's Hammer heals 100% more frequently and generates 1 Holy Power every 4 seconds. Holy Prism's healing is increased by 40% and it generates 1 Holy Power if cast on an enemy target, or 3 if cast on an ally.
This tier set will have a strong impact on our stat priority, talents and playstyle just like it did in Season 2. Holy Shock will once again be a powerful source of spot healing, allowing us to lean more heavily into Shield of the Righteous usage in Mythic+ and Light of Dawn in raid.
Playing around this tier set will simply mean pressing Light's Hammer / Holy Prism on cooldown and throwing out as many Holy Shocks as possible. Your default pick should always be Light's Hammer in raid as it will provide the most throughput, while in Mythic+ you should default to Holy Prism for the increased spot healing and on demand AoE burst.
Dragonflight reduced the amount of on use player enhancements by removing armor kits and replacing them with permanent leg enchants. Additionally, weapon oils were replaced with runes and flasks were replaced with phials. Before every dungeon or raid boss you'll need to make sure you have everything reapplied to your armor so I suggest getting a weakaura like this to remind you if any of your consumables are missing.